Biopharma Board Governance
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Board Dynamics & Effectiveness

The human and organizational dimensions of board governance

Board Dynamics & Effectiveness16 min read

Governance During Crisis: Data Fraud, Safety Signals, and Scandal

The board's playbook when things go catastrophically wrong — the first 48 hours, the communication architecture, and the work of recovery. With reference cases from torcetrapib, Cassava Sciences, and Insys Therapeutics.

|Lawrence Fine
Board Dynamics & Effectiveness13 min read

Building a Culture of Constructive Dissent in the Boardroom

Groupthink is the silent killer of biopharma boards. Building a culture where honest disagreement is normal is one of the most consequential governance investments a board can make.

|Lawrence Fine
Board Dynamics & Effectiveness12 min read

Founder-CEO Dynamics on Venture-Backed Boards

When the scientific founder is also the chief executive, the board faces a distinctive set of governance challenges. The standard playbook does not quite fit.

|Lawrence Fine
Board Dynamics & Effectiveness12 min read

When the Board Needs to Replace the CEO Mid-Trial

The governance process for the hardest leadership decision a biopharma board will ever make — and how to execute it without destroying the company in the process.

|Lawrence Fine
Board Dynamics & Effectiveness11 min read

Managing Conflicts of Interest on Biopharma Boards

Disclosure, recusal, and the gray areas that governance policies don't cover — a practical guide for directors navigating competing interests.

|Lawrence Fine
Board Dynamics & Effectiveness11 min read

The Politics of Small Boards

When interpersonal dynamics have outsized impact — navigating alliances, grudges, and power in a five-person room.

|Lawrence Fine
Board Dynamics & Effectiveness11 min read

CEO Succession Planning for Clinical-Stage Companies

Why biopharma companies need succession plans earlier than most boards think — and how to build one that actually works.

|Lawrence Fine
Board Dynamics & Effectiveness9 min read

Board Self-Assessment That Actually Improves Performance

Why most board evaluations are theater — and what an honest self-assessment process looks like in a clinical-stage biopharma company.

|Lawrence Fine
Board Dynamics & Effectiveness8 min read

Handling an Underperforming Board Member

The difficult conversation most biopharma boards avoid — and the governance framework for actually addressing it.

|Lawrence Fine
Board Dynamics & Effectiveness8 min read

CEO Evaluation in a Clinical-Stage Company

Evaluating a CEO against quarterly revenue targets is straightforward. Evaluating one who is managing clinical risk, investor relationships, and a science-driven team — without any product on the market — is something else entirely.

|Lawrence Fine
Board Dynamics & Effectiveness9 min read

Managing the Tension Between Investor and Independent Directors

The structural conflict between investor directors and independent directors is the defining governance challenge of venture-backed biopharma boards. Here is how it manifests and how to manage it.

|Lawrence Fine